Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization
Abstract HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis.Studies have shown that the association of Treatments - Hot - Cold Nef with the inner leaflet of the plasma membrane and with endocytic and perinuclear vesicles is essential for most activities of Nef.Using purified recombinant proteins in pull-down assays and by co-immu